Leading Articles

How to Titrate Vasopressors Against Fluid Loading in Septic Shock  PDF    CME

Benoît Vallet, MD, Hervé Tytgat, MD, and Gilles Lebuffe, MD

The initial management of patients with septic shock includes ensuring oxygen supply, fluid therapy, consideration of inotrope or vasopressor therapy, and specific treatments to address the cause... Read More >>

Immunoglobulins in Sepsis  PDF    CME

Giorgio Berlot, MD, Barbara Bacer, MD, Marco Piva, MD, Umberto Lucangelo, MD, and Marino Viviani, MD

Polyclonal intravenous immunoglobulins (IvIgs) are frequently used in critically ill septic patients even though the clinical studies demonstrating their efficacy and safety are relatively small when compared with those performed using other drugs... Read More >>

High-Volume Hemofiltration as Adjunctive Therapy for Sepsis and Systemic Inflammatory Response Syndrome: Background, Definition and a Descriptive Analysis of Animal and Human Studies  PDF    CME

Catherine SC Bouman, MD, PhD

The application of high-volume hemofiltration (HV-HF) as adjunctive therapy in severe sepsis or systemic inflammatory response syndrome (SIRS) may improve outcome in critically ill patients, although this hypothesis remains a subject of significant debate... Read More >>




Clinical Reviews
Case Studies Commentary and analysis on recent key papers

Meeting Reports

36th Critical Care Congress of the Society of Critical Care Medicine (SCCM)  PDF    

Timothy D Girard, MD, MSCI

The Society of Critical Care Medicine (SCCM) hosted its 36th Critical Care Congress in Orlando, FL, USA, in February, and sepsis was a focal point of numerous research and educational presentations... Read More >>



SMART
In this month's SMART:
  • Crucial Presentations from the Scandinavian Society of Anaesthesiology and Intensive Care Medicine.
  • Research and treatment in pediatric sepsis.
  • Key papers and news from the world media.
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Advances in Sepsis, SMART™, and SMARTbot™ are supported by educational grants from Eli Lilly and Company, Acute Care. Certain authors and editors may have financial or other relationships with Eli Lilly and Company. Some of the information/data reported here for drugs/devices discussed may differ from information/data contained in the prescribing information approved by regulatory authorities in specific countries. For approved information and uses for drugs/devices discussed, please consult the manufacturer's prescribing information.

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